Parkinsonism, tremor, and depression induced by cinnarizine and flunarizine.
نویسندگان
چکیده
Comment Both these patients were positive for HIV antibody and had a clinical and radiological presentation suggestive of P carinni pneumonia that responded to treatment; thus the criteria fbr a diagnosis of AIDS were satisfied. ' In case 2 the diagnosis was complicated by the previous amiodarone treatment, though pneumonitis induced by amiodarone is unusual at a daily dosage less than 400 mg.23 Chest infections are common in the elderly. The increasing incidence of HIV infection and a reluctance of older homosexuals to admit to at risk behaviour may mean that elderly patients will die without AIDS being diagnosed. In the United States 10% of patients with AIDS are over 50, 2-5% over 60, and 0 4% over 70. The table shows the age distribution of our patients with AIDS up to October 1987. Six of 235 (2 5%) patients were over 60. P carinii pneumonia should be considered in all patients with atypical chest infections, even when there are no apparent risk factors.
منابع مشابه
Flunarizine and cinnarizine-induced parkinsonism: 25 years of de Melo-Souza's syndrome.
Drug-induced Parkinsonism (DIP) is the second most common cause of parkinsonism (PK). Flunarizine and cinnarizine induced parkinsonism (FCIP) is one of the most frequent forms and is commonly found in elderly female patients manifesting symmetrical motor symptoms with resting and/or postural tremor, often associated with depression, and occasionally acathisia and dyskinesia . FCIP was first des...
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BACKGROUND Drug-Induced Parkinsonism (DIP) represents the second leading cause of Parkinsonism (PK) in several countries. Flunarizine and cinnarizine are some of the most common drugs that cause DIP. This paper reviews the first description of Flunarizine and Cinnarizine-Induced Parkinsonism (FCIP), as well as the subsequent literature, emphasizing epidemiological, clinical and diagnostic aspec...
متن کاملParkinsonism and other movement disorders in outpatients in chronic use of cinnarizine and flunarizine.
The purpose of this study is to determine the prevalence and the patterns of movement disorders (MD) in outpatients submitted to the chronic use of cinnarizine (cz) or flunarizine (fz), and to establish the main risk factors for MD development. Over a period of 3 months, data were collected from outpatients who were chronic users of cz or fz in a municipal health institute. A total of 26 outpat...
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ورودعنوان ژورنال:
- BMJ
دوره 297 6650 شماره
صفحات -
تاریخ انتشار 1988